gehan                  package:MASS                  R Documentation

Remission Times of Leukaemia Patients

Description:

     A data frame from a trial of 42 leukaemia patients. Some were
     treated with the drug _6-mercaptopurine_ and the rest are
     controls.  The trial was designed as matched pairs, both withdrawn
     from the trial when either came out of remission.

Usage:

     gehan

Format:

     This data frame contains the following columns:

     'pair' label for pair.

     'time' remission time in weeks.

     'cens' censoring, 0/1.

     'treat' treatment, control or 6-MP.


Source:

     Cox, D. R. and Oakes, D. (1984) _Analysis of Survival Data._
     Chapman & Hall, p. 7. Taken from

     Gehan, E.A. (1965) A generalized Wilcoxon test for comparing
     arbitrarily single-censored samples. _Biometrika_ *52*, 203-233.

References:

     Venables, W. N. and Ripley, B. D. (2002) _Modern Applied
     Statistics with S._ Fourth edition.  Springer.

Examples:

     library(survival)
     gehan.surv <- survfit(Surv(time, cens) ~ treat, data = gehan,
          conf.type = "log-log")
     summary(gehan.surv)
     survreg(Surv(time, cens) ~ factor(pair) + treat, gehan, dist = "exponential")
     summary(survreg(Surv(time, cens) ~ treat, gehan, dist = "exponential"))
     summary(survreg(Surv(time, cens) ~ treat, gehan))
     gehan.cox <- coxph(Surv(time, cens) ~ treat, gehan)
     summary(gehan.cox)

