PBG                   package:nlme                   R Documentation

Effect of Phenylbiguanide on Blood Pressure

Description:

     The 'PBG' data frame has 60 rows and 5 columns.

Format:

     This data frame contains the following columns:

     deltaBP a numeric vector

     dose a numeric vector

     Run an ordered factor with levels 'T5' < 'T4' < 'T3' < 'T2' < 'T1'
          < 'P5' < 'P3' < 'P2' < 'P4' < 'P1'

     Treatment a factor with levels 'MDL 72222'  'Placebo' 

     Rabbit an ordered factor with levels '5' < '3' < '2' < '4' < '1'


Details:

     Data on an experiment to examine the effect of a antagonist MDL
     72222 on the change in blood pressure experienced with increasing
     dosage of phenylbiguanide are described in Ludbrook (1994) and
     analyzed in Venables and Ripley (1999, section 8.8).  Each of five
     rabbits was exposed to increasing doses of phenylbiguanide after
     having either a placebo or the HD5-antagonist MDL 72222
     administered.

Source:

     Pinheiro, J. C. and Bates, D. M. (2000), _Mixed-Effects Models in
     S and S-PLUS_, Springer, New York.  (Appendix A.21)

     Venables, W. N. and Ripley, B. D. (1999) _Modern Applied
     Statistics with S-PLUS (3rd ed)_, Springer, New York.

     Ludbrook, J. (1994), Repeated measurements and multiple
     comparisons in cardiovascular research, _Cardiovascular Research_,
     *28*, 303-311.

