# electronic Ligand Builder and Optimisation Workbench (eLBOW)
#   - a module of PHENIX version 1.18.1-3865-
#   - file written: Tue Jun 16 02:40:31 2020
#   Inital geometry file: a 171 line input string
#   Ligand name: "(1~{R},3~{S},5~{Z})-5-[(2~{E})-2-[(1~{R},3~{a}~{S},7~{a}~{R})-7~{a}-methyl-1-[(1~{S})-1-[(2~{S},5~{S})-5-(2-oxidanylpropan-2-yl)oxolan-2-yl]ethyl]-2,3,3~{a},5,6,7-hexahydro-1~{H}-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol"
#   Quantum optimisation: True
#   Method: PBEh-3c
#   Random seed: 3628800
#   SMILES string: C[C@H]([C@@H]1CC[C@H](O1)C(C)(C)O)[C@H]2CC[C@H]3/C(CCC[C@]23C)=C/C=C4/C[C@@H](O)C[C@H](O)C4=C
#
data_comp_list
loop_
_chem_comp.id
_chem_comp.three_letter_code
_chem_comp.name
_chem_comp.group
_chem_comp.number_atoms_all
_chem_comp.number_atoms_nh
_chem_comp.desc_level
_chem_comp.initial_date
_chem_comp.modified_date
_chem_comp.source
 9CW  9CW  "(1~{R},3~{S},5~{Z})-5-[(2~{E})-2-[(1~{R},3~{a}~{S},7~{a}~{R})-7~{a}-methyl-1-[(1~{S})-1-[(2~{S},5~{S})-5-(2-oxidanylpropan-2-yl)oxolan-2-yl]ethyl]-2,3,3~{a},5,6,7-hexahydro-1~{H}-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol"
  ligand  76  32  .  2022-07-24  2022-07-26
;
Directly from eLBOW using geometry from QM method PBEh-3c with CPCM solvent model
Validated by Mogul as OK (reasonable std)
;

data_comp_9CW
loop_
_chem_comp_atom.comp_id
_chem_comp_atom.atom_id
_chem_comp_atom.type_symbol
_chem_comp_atom.type_energy
_chem_comp_atom.charge
_chem_comp_atom.partial_charge
_chem_comp_atom.x
_chem_comp_atom.y
_chem_comp_atom.z
 9CW  O3   O  OH1   0  -0.664  -5.3449   2.1007  -1.0338
 9CW  C25  C  CH1   0  -0.028  -5.9269   2.1111   0.2565
 9CW  C24  C  CH2   0  -0.488  -7.3376   1.5535   0.1282
 9CW  C23  C  CH1   0   0.072  -7.3405   0.0798  -0.2502
 9CW  O2   O  OH1   0  -0.674  -8.6872  -0.3467  -0.2891
 9CW  C22  C  CH2   0  -0.533  -6.5218  -0.7307   0.7581
 9CW  C26  C  C     0   0.068  -5.1081   1.2699   1.2091
 9CW  C27  C  C2    0  -0.588  -4.4661   1.8168   2.2398
 9CW  C21  C  C     0   0.097  -5.1319  -0.1748   0.9143
 9CW  C20  C  C1    0  -0.301  -4.0432  -0.9460   0.7518
 9CW  C19  C  C1    0  -0.356  -2.6609  -0.5107   0.7953
 9CW  C15  C  C     0   0.153  -1.5822  -1.2982   0.6561
 9CW  C2   C  CH1   0  -0.244  -0.1788  -0.7801   0.6535
 9CW  C16  C  CH2   0  -0.506  -1.6067  -2.7876   0.4497
 9CW  C17  C  CH2   0  -0.432  -0.8488  -3.1764  -0.8243
 9CW  C18  C  CH2   0  -0.416   0.5578  -2.5793  -0.8943
 9CW  C1   C  CT    0  -0.063   0.5518  -1.0630  -0.6850
 9CW  C    C  CH3   0  -0.676  -0.1344  -0.3531  -1.8532
 9CW  C5   C  CH1   0  -0.165   1.9247  -0.4132  -0.3799
 9CW  C4   C  CH2   0  -0.460   1.5556   0.8690   0.4113
 9CW  C3   C  CH2   0  -0.450   0.1223   0.6805   0.9452
 9CW  C6   C  CH1   0  -0.273   2.8775  -0.1293  -1.5538
 9CW  C14  C  CH3   0  -0.674   3.2323  -1.3846  -2.3471
 9CW  C7   C  CH1   0   0.076   4.1275   0.6040  -1.0621
 9CW  C13  C  CH2   0  -0.468   5.1241   1.0810  -2.1106
 9CW  C12  C  CH2   0  -0.503   6.3814   1.2624  -1.2654
 9CW  C8   C  CH1   0   0.064   6.2477   0.1550  -0.2119
 9CW  O    O  O2    0  -0.511   4.8870  -0.2444  -0.2127
 9CW  C9   C  CT    0   0.182   6.7028   0.5418   1.2079
 9CW  C11  C  CH3   0  -0.673   6.6331  -0.6779   2.1248
 9CW  O1   O  OH1   0  -0.676   8.0390   1.0204   1.1294
 9CW  C10  C  CH3   0  -0.677   5.8706   1.6719   1.7989
 9CW  H1   H  HOH1  0   0.449  -4.4353   2.4050  -0.9547
 9CW  H2   H  HCH1  0   0.226  -5.9861   3.1356   0.6477
 9CW  H3   H  HCH2  0   0.237  -7.8452   1.6808   1.0894
 9CW  H4   H  HCH2  0   0.250  -7.8966   2.1376  -0.6086
 9CW  H5   H  HCH1  0   0.206  -6.8775  -0.0368  -1.2389
 9CW  H6   H  HOH1  0   0.449  -8.7048  -1.2504  -0.6193
 9CW  H7   H  HCH2  0   0.236  -7.0439  -0.6958   1.7228
 9CW  H8   H  HCH2  0   0.245  -6.4776  -1.7798   0.4526
 9CW  H9   H  H     0   0.246  -3.8996   1.2218   2.9450
 9CW  H10  H  H     0   0.243  -4.5030   2.8847   2.4206
 9CW  H11  H  H     0   0.232  -4.2245  -1.9927   0.5287
 9CW  H12  H  H     0   0.227  -2.5018   0.5516   0.9372
 9CW  H13  H  HCH1  0   0.231   0.3659  -1.3734   1.4054
 9CW  H14  H  HCH2  0   0.231  -1.1185  -3.2621   1.3096
 9CW  H15  H  HCH2  0   0.244  -2.6187  -3.1897   0.4102
 9CW  H16  H  HCH2  0   0.233  -0.7859  -4.2652  -0.8890
 9CW  H17  H  HCH2  0   0.221  -1.4299  -2.8543  -1.6924
 9CW  H18  H  HCH2  0   0.212   1.1877  -3.0385  -0.1234
 9CW  H19  H  HCH2  0   0.230   0.9983  -2.8482  -1.8548
 9CW  H20  H  HCH3  0   0.237  -1.1928  -0.6042  -1.9270
 9CW  H21  H  HCH3  0   0.231  -0.0704   0.7327  -1.7673
 9CW  H22  H  HCH3  0   0.228   0.3316  -0.6291  -2.8009
 9CW  H23  H  HCH1  0   0.218   2.4419  -1.1004   0.3015
 9CW  H24  H  HCH2  0   0.239   2.2692   1.0416   1.2183
 9CW  H25  H  HCH2  0   0.222   1.6060   1.7491  -0.2348
 9CW  H26  H  HCH2  0   0.221  -0.5685   1.3444   0.4206
 9CW  H27  H  HCH2  0   0.234   0.0336   0.9115   2.0079
 9CW  H28  H  HCH1  0   0.222   2.3775   0.5770  -2.2288
 9CW  H29  H  HCH3  0   0.229   2.3748  -1.7592  -2.9029
 9CW  H30  H  HCH3  0   0.231   4.0123  -1.1928  -3.0837
 9CW  H31  H  HCH3  0   0.219   3.5843  -2.1882  -1.6987
 9CW  H32  H  HCH1  0   0.219   3.8072   1.4924  -0.4988
 9CW  H33  H  HCH2  0   0.230   5.2854   0.3298  -2.8864
 9CW  H34  H  HCH2  0   0.240   4.7992   2.0014  -2.5966
 9CW  H35  H  HCH2  0   0.247   7.2999   1.1683  -1.8432
 9CW  H36  H  HCH2  0   0.237   6.3875   2.2532  -0.8080
 9CW  H37  H  HCH1  0   0.209   6.8486  -0.7149  -0.5198
 9CW  H38  H  HCH3  0   0.231   6.9913  -0.4281   3.1252
 9CW  H39  H  HCH3  0   0.231   5.6122  -1.0483   2.2161
 9CW  H40  H  HCH3  0   0.224   7.2473  -1.4969   1.7403
 9CW  H41  H  HOH1  0   0.442   8.6003   0.3049   0.8108
 9CW  H42  H  HCH3  0   0.235   6.2259   1.9115   2.8027
 9CW  H43  H  HCH3  0   0.232   5.9198   2.5847   1.2031
 9CW  H44  H  HCH3  0   0.237   4.8248   1.3766   1.8807

loop_
_chem_comp_bond.comp_id
_chem_comp_bond.atom_id_1
_chem_comp_bond.atom_id_2
_chem_comp_bond.type
_chem_comp_bond.value_dist
_chem_comp_bond.value_dist_esd
_chem_comp_bond.value_dist_neutron
 9CW  C10  C9   single  1.523  0.020  1.523
 9CW  C12  C8   single  1.534  0.020  1.534
 9CW  C12  C13  single  1.526  0.020  1.526
 9CW  C9   C11  single  1.528  0.020  1.528
 9CW  C9   O1   single  1.421  0.020  1.421
 9CW  C9   C8   single  1.540  0.020  1.540
 9CW  C8   O    single  1.418  0.020  1.418
 9CW  C13  C7   single  1.523  0.020  1.523
 9CW  O    C7   single  1.421  0.020  1.421
 9CW  C7   C6   single  1.530  0.020  1.530
 9CW  C    C1   single  1.530  0.020  1.530
 9CW  C6   C14  single  1.527  0.020  1.527
 9CW  C6   C5   single  1.538  0.020  1.538
 9CW  C27  C26  double  1.332  0.020  1.332
 9CW  C17  C18  single  1.530  0.020  1.530
 9CW  C17  C16  single  1.533  0.020  1.533
 9CW  C18  C1   single  1.531  0.020  1.531
 9CW  C1   C5   single  1.549  0.020  1.549
 9CW  C1   C2   single  1.551  0.020  1.551
 9CW  C24  C25  single  1.522  0.020  1.522
 9CW  C24  C23  single  1.522  0.020  1.522
 9CW  O3   C25  single  1.416  0.020  1.416
 9CW  C26  C21  single  1.475  0.020  1.475
 9CW  C26  C25  single  1.512  0.020  1.512
 9CW  C5   C4   single  1.551  0.020  1.551
 9CW  C22  C21  single  1.505  0.020  1.505
 9CW  C22  C23  single  1.531  0.020  1.531
 9CW  C21  C20  double  1.344  0.020  1.344
 9CW  C20  C19  single  1.450  0.020  1.450
 9CW  C23  O2   single  1.413  0.020  1.413
 9CW  C4   C3   single  1.541  0.020  1.541
 9CW  C16  C15  single  1.504  0.020  1.504
 9CW  C19  C15  double  1.343  0.020  1.343
 9CW  C15  C2   single  1.496  0.020  1.496
 9CW  C2   C3   single  1.520  0.020  1.520
 9CW  O3   H1   single  0.850  0.020  0.980
 9CW  C25  H2   single  0.970  0.020  1.090
 9CW  C24  H3   single  0.970  0.020  1.090
 9CW  C24  H4   single  0.970  0.020  1.090
 9CW  C23  H5   single  0.970  0.020  1.090
 9CW  O2   H6   single  0.850  0.020  0.980
 9CW  C22  H7   single  0.970  0.020  1.090
 9CW  C22  H8   single  0.970  0.020  1.090
 9CW  C27  H9   single  0.930  0.020  1.080
 9CW  C27  H10  single  0.930  0.020  1.080
 9CW  C20  H11  single  0.930  0.020  1.080
 9CW  C19  H12  single  0.930  0.020  1.080
 9CW  C2   H13  single  0.970  0.020  1.090
 9CW  C16  H14  single  0.970  0.020  1.090
 9CW  C16  H15  single  0.970  0.020  1.090
 9CW  C17  H16  single  0.970  0.020  1.090
 9CW  C17  H17  single  0.970  0.020  1.090
 9CW  C18  H18  single  0.970  0.020  1.090
 9CW  C18  H19  single  0.970  0.020  1.090
 9CW  C    H20  single  0.970  0.020  1.090
 9CW  C    H21  single  0.970  0.020  1.090
 9CW  C    H22  single  0.970  0.020  1.090
 9CW  C5   H23  single  0.970  0.020  1.090
 9CW  C4   H24  single  0.970  0.020  1.090
 9CW  C4   H25  single  0.970  0.020  1.090
 9CW  C3   H26  single  0.970  0.020  1.090
 9CW  C3   H27  single  0.970  0.020  1.090
 9CW  C6   H28  single  0.970  0.020  1.090
 9CW  C14  H29  single  0.970  0.020  1.090
 9CW  C14  H30  single  0.970  0.020  1.090
 9CW  C14  H31  single  0.970  0.020  1.090
 9CW  C7   H32  single  0.970  0.020  1.090
 9CW  C13  H33  single  0.970  0.020  1.090
 9CW  C13  H34  single  0.970  0.020  1.090
 9CW  C12  H35  single  0.970  0.020  1.090
 9CW  C12  H36  single  0.970  0.020  1.090
 9CW  C8   H37  single  0.970  0.020  1.090
 9CW  C11  H38  single  0.970  0.020  1.090
 9CW  C11  H39  single  0.970  0.020  1.090
 9CW  C11  H40  single  0.970  0.020  1.090
 9CW  O1   H41  single  0.850  0.020  0.980
 9CW  C10  H42  single  0.970  0.020  1.090
 9CW  C10  H43  single  0.970  0.020  1.090
 9CW  C10  H44  single  0.970  0.020  1.090

loop_
_chem_comp_angle.comp_id
_chem_comp_angle.atom_id_1
_chem_comp_angle.atom_id_2
_chem_comp_angle.atom_id_3
_chem_comp_angle.value_angle
_chem_comp_angle.value_angle_esd
 9CW  H1   O3   C25  108.14  3.000
 9CW  H2   C25  C26  108.89  3.000
 9CW  H2   C25  C24  108.77  3.000
 9CW  C26  C25  C24  110.56  3.000
 9CW  H2   C25  O3   110.71  3.000
 9CW  C26  C25  O3   110.34  3.000
 9CW  C24  C25  O3   107.55  3.000
 9CW  H4   C24  H3   107.00  3.000
 9CW  H4   C24  C23  110.41  3.000
 9CW  H3   C24  C23  109.28  3.000
 9CW  H4   C24  C25  109.55  3.000
 9CW  H3   C24  C25  108.25  3.000
 9CW  C23  C24  C25  112.18  3.000
 9CW  H5   C23  C22  108.14  3.000
 9CW  H5   C23  O2   110.19  3.000
 9CW  C22  C23  O2   111.59  3.000
 9CW  H5   C23  C24  109.03  3.000
 9CW  O2   C23  C24  107.52  3.000
 9CW  C22  C23  C24  110.36  3.000
 9CW  H6   O2   C23  108.08  3.000
 9CW  H8   C22  H7   107.17  3.000
 9CW  H8   C22  C21  110.24  3.000
 9CW  H7   C22  C21  109.65  3.000
 9CW  H8   C22  C23  110.21  3.000
 9CW  H7   C22  C23  107.92  3.000
 9CW  C21  C22  C23  111.51  3.000
 9CW  C21  C26  C27  124.39  3.000
 9CW  C21  C26  C25  114.23  3.000
 9CW  C27  C26  C25  121.35  3.000
 9CW  H10  C27  H9   116.79  3.000
 9CW  H10  C27  C26  121.15  3.000
 9CW  H9   C27  C26  122.05  3.000
 9CW  C20  C21  C26  124.98  3.000
 9CW  C20  C21  C22  121.57  3.000
 9CW  C26  C21  C22  113.42  3.000
 9CW  H11  C20  C19  117.06  3.000
 9CW  H11  C20  C21  116.29  3.000
 9CW  C19  C20  C21  126.61  3.000
 9CW  H12  C19  C15  118.07  3.000
 9CW  H12  C19  C20  116.00  3.000
 9CW  C15  C19  C20  125.92  3.000
 9CW  C16  C15  C2   110.98  3.000
 9CW  C2   C15  C19  123.41  3.000
 9CW  C16  C15  C19  125.59  3.000
 9CW  H13  C2   C3   106.78  3.000
 9CW  H13  C2   C1   104.94  3.000
 9CW  C3   C2   C1   104.34  3.000
 9CW  H13  C2   C15  106.03  3.000
 9CW  C3   C2   C15  121.23  3.000
 9CW  C1   C2   C15  112.35  3.000
 9CW  H15  C16  H14  106.39  3.000
 9CW  H15  C16  C17  109.60  3.000
 9CW  H14  C16  C17  108.77  3.000
 9CW  H15  C16  C15  112.68  3.000
 9CW  H14  C16  C15  108.28  3.000
 9CW  C17  C16  C15  110.94  3.000
 9CW  H17  C17  H16  106.09  3.000
 9CW  H17  C17  C18  109.72  3.000
 9CW  H16  C17  C18  109.47  3.000
 9CW  H17  C17  C16  108.81  3.000
 9CW  H16  C17  C16  109.31  3.000
 9CW  C18  C17  C16  113.19  3.000
 9CW  H19  C18  H18  106.50  3.000
 9CW  H19  C18  C1   111.49  3.000
 9CW  H18  C18  C1   108.73  3.000
 9CW  H19  C18  C17  108.39  3.000
 9CW  H18  C18  C17  109.43  3.000
 9CW  C1   C18  C17  112.13  3.000
 9CW  C5   C1   C    110.69  3.000
 9CW  C5   C1   C18  116.03  3.000
 9CW  C    C1   C18  110.92  3.000
 9CW  C5   C1   C2    99.84  3.000
 9CW  C18  C1   C2   107.49  3.000
 9CW  C    C1   C2   111.30  3.000
 9CW  H22  C    H21  107.15  3.000
 9CW  H22  C    H20  107.31  3.000
 9CW  H21  C    H20  106.95  3.000
 9CW  H22  C    C1   110.74  3.000
 9CW  H21  C    C1   112.05  3.000
 9CW  H20  C    C1   112.35  3.000
 9CW  H23  C5   C6   107.31  3.000
 9CW  H23  C5   C4   108.24  3.000
 9CW  C6   C5   C4   112.58  3.000
 9CW  H23  C5   C1   106.10  3.000
 9CW  C4   C5   C1   103.67  3.000
 9CW  C6   C5   C1   118.43  3.000
 9CW  H25  C4   H24  106.24  3.000
 9CW  H25  C4   C3   110.25  3.000
 9CW  H24  C4   C3   111.80  3.000
 9CW  H25  C4   C5   110.68  3.000
 9CW  H24  C4   C5   110.63  3.000
 9CW  C3   C4   C5   107.27  3.000
 9CW  H27  C3   H26  106.72  3.000
 9CW  H27  C3   C4   112.78  3.000
 9CW  H26  C3   C4   110.33  3.000
 9CW  H27  C3   C2   111.98  3.000
 9CW  H26  C3   C2   111.51  3.000
 9CW  C4   C3   C2   103.61  3.000
 9CW  H28  C6   C7   105.15  3.000
 9CW  H28  C6   C14  108.39  3.000
 9CW  C7   C6   C14  111.79  3.000
 9CW  H28  C6   C5   107.81  3.000
 9CW  C14  C6   C5   112.87  3.000
 9CW  C7   C6   C5   110.44  3.000
 9CW  H31  C14  H30  107.48  3.000
 9CW  H31  C14  H29  107.72  3.000
 9CW  H30  C14  H29  106.21  3.000
 9CW  H31  C14  C6   111.83  3.000
 9CW  H30  C14  C6   111.88  3.000
 9CW  H29  C14  C6   111.43  3.000
 9CW  H32  C7   O    109.38  3.000
 9CW  H32  C7   C13  106.87  3.000
 9CW  O    C7   C13  104.41  3.000
 9CW  H32  C7   C6   108.29  3.000
 9CW  O    C7   C6   110.04  3.000
 9CW  C13  C7   C6   117.60  3.000
 9CW  H34  C13  H33  107.94  3.000
 9CW  H34  C13  C12  113.08  3.000
 9CW  H33  C13  C12  110.71  3.000
 9CW  H34  C13  C7   112.10  3.000
 9CW  H33  C13  C7   111.73  3.000
 9CW  C12  C13  C7   101.25  3.000
 9CW  H36  C12  H35  107.22  3.000
 9CW  H36  C12  C8   111.59  3.000
 9CW  H35  C12  C8   112.05  3.000
 9CW  H36  C12  C13  110.17  3.000
 9CW  H35  C12  C13  113.00  3.000
 9CW  C8   C12  C13  102.87  3.000
 9CW  H37  C8   C9   107.15  3.000
 9CW  H37  C8   O    107.51  3.000
 9CW  C9   C8   O    110.78  3.000
 9CW  H37  C8   C12  109.30  3.000
 9CW  O    C8   C12  106.65  3.000
 9CW  C9   C8   C12  115.21  3.000
 9CW  C8   O    C7   110.19  3.000
 9CW  C10  C9   O1   106.57  3.000
 9CW  O1   C9   C11  110.18  3.000
 9CW  C10  C9   C11  109.55  3.000
 9CW  O1   C9   C8   108.15  3.000
 9CW  C11  C9   C8   109.83  3.000
 9CW  C10  C9   C8   112.49  3.000
 9CW  H40  C11  H39  107.53  3.000
 9CW  H40  C11  H38  108.02  3.000
 9CW  H39  C11  H38  107.96  3.000
 9CW  H40  C11  C9   111.18  3.000
 9CW  H39  C11  C9   111.37  3.000
 9CW  H38  C11  C9   110.63  3.000
 9CW  H41  O1   C9   108.41  3.000
 9CW  H44  C10  H43  108.12  3.000
 9CW  H44  C10  H42  107.63  3.000
 9CW  H43  C10  H42  107.69  3.000
 9CW  H44  C10  C9   110.64  3.000
 9CW  H43  C10  C9   112.60  3.000
 9CW  H42  C10  C9   109.99  3.000

loop_
_chem_comp_tor.comp_id
_chem_comp_tor.id
_chem_comp_tor.atom_id_1
_chem_comp_tor.atom_id_2
_chem_comp_tor.atom_id_3
_chem_comp_tor.atom_id_4
_chem_comp_tor.value_angle
_chem_comp_tor.value_angle_esd
_chem_comp_tor.period
 9CW  Var_01  C22  C21  C26  C25  -51.30  30.0  1
 9CW  Var_02  C26  C21  C22  C23   52.12  30.0  1
 9CW  Var_03  C18  C17  C16  C15   51.37  30.0  1
 9CW  Var_04  C17  C16  C15  C2   -54.58  30.0  1
 9CW  Var_05  C5   C4   C3   C2     9.58  30.0  1
 9CW  Var_06  C1   C18  C17  C16  -52.76  30.0  1
 9CW  Var_07  C8   C12  C13  C7    33.30  30.0  1
 9CW  Var_08  C19  C20  C21  C22  175.96  30.0  2
 9CW  Var_09  C15  C19  C20  C21  178.66  30.0  2
 9CW  Var_10  C16  C15  C19  C20   -1.02  30.0  2
 9CW  Var_11  H9   C27  C26  C25  178.24  30.0  2
 9CW  Var_12  H42  C10  C9   C8   179.92  30.0  3
 9CW  Var_13  H38  C11  C9   C8   177.72  30.0  3

loop_
_chem_comp_chir.comp_id
_chem_comp_chir.id
_chem_comp_chir.atom_id_centre
_chem_comp_chir.atom_id_1
_chem_comp_chir.atom_id_2
_chem_comp_chir.atom_id_3
_chem_comp_chir.volume_sign
 9CW  chir_01  C25  C24  O3   C26  positiv
 9CW  chir_02  C23  O2   C22  C24  positiv
 9CW  chir_03  C2   C1   C15  C3   positiv
 9CW  chir_04  C1   C18  C5   C2   positiv
 9CW  chir_05  C5   C4   C1   C6   negativ
 9CW  chir_06  C6   C5   C14  C7   positiv
 9CW  chir_07  C7   O    C13  C6   negativ
 9CW  chir_08  C8   O    C12  C9   negativ

