B ‰°b{ã@s dZddlZdd„Zdd„ZdS)zLocal Composition Complexity.éNc Cspt d¡}t|ƒ}t|ƒ ¡}dg}dg}x@t|ƒD]4}| |dt|ƒt |dt|ƒ¡|¡q4W|d|…}| d¡} | d¡} | d¡} | d¡} || } || }|| }|| }| | ||| ¡|d}xˆt||ƒD]v}||d||d…}||dkr.| |d¡n2|dkrü| d8} |  d¡r~| d7} || } || }| | ||| ¡nz|  d¡r¼| d7} || } || }| | ||| ¡n<|  d¡r`| d7} || } || }| | ||| ¡nd|dkrÊ| d8} |  d¡rL| d7} || } || }| | ||| ¡nz|  d¡rŠ| d7} || }|| }| | ||| ¡n<|  d¡r`| d7} || }|| }| | ||| ¡n–|dkr–| d8} |  d¡r| d7} || } || }| | ||| ¡nz|  d¡rX| d7} || }|| }| | ||| ¡n<|  d¡r`| d7} || }|| }| | ||| ¡nÊ|dkr`| d8} |  d¡ræ| d7} || } || }| | ||| ¡nz|  d¡r$| d7} || }|| }| | ||| ¡n<|  d¡r`| d7} || }|| }| | ||| ¡|d}qðW|S) aÚCalculate Local Composition Complexity (LCC) values over sliding window. Returns a list of floats, the LCC values for a sliding window over the sequence. seq - an unambiguous DNA sequence (a string or Seq object) wsize - window size, integer The result is the same as applying lcc_simp multiple times, but this version is optimized for speed. The optimization works by using the value of previous window as a base to compute the next one. éréÚAÚCÚTÚGéÿÿÿÿ) ÚmathÚlogÚlenÚstrÚupperÚrangeÚappendÚfloatÚcountÚendswith)ÚseqÚwsizeÚl2Ztamseqr ZcomponeZlccsalÚiZwindowZcant_aZcant_cZcant_tZcant_gÚterm_aÚterm_cÚterm_tÚterm_gÚtailÚx©rú/lib/python3.7/site-packages/Bio/SeqUtils/lcc.pyÚlcc_mult sº  0                      rcCs t|ƒ}t|ƒ ¡}t d¡}d|kr,d}n.| d¡t|ƒt | d¡t|ƒ¡|}d|krhd}n.| d¡t|ƒt | d¡t|ƒ¡|}d|kr¤d}n.| d¡t|ƒt | d¡t|ƒ¡|}d|kràd}n.| d¡t|ƒt | d¡t|ƒ¡|}|||| S)abCalculate Local Composition Complexity (LCC) for a sequence. seq - an unambiguous DNA sequence (a string or Seq object) Returns the Local Composition Complexity (LCC) value for the entire sequence (as a float). Reference: Andrzej K Konopka (2005) Sequence Complexity and Composition https://doi.org/10.1038/npg.els.0005260 rrrrrr)r r r r r rr)rrr rrrrrrrrÚlcc_simpzs(   r )Ú__doc__r rr rrrrÚsm