go.id go.term Definition Ontology pvalue count.InDataset count.InGenome totaltermInDataset totaltermInGenome BH.adjusted.p.value GO:0006333 chromatin assembly or disassembly The formation or destruction of chromatin structures. BP 2.66377639857441e-06 6 185 2830 1389949 0.00306600663475915 GO:0006334 nucleosome assembly The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA. BP 1.32608381089436e-05 5 144 2830 1389949 0.00656404360012351 GO:0031497 chromatin assembly The assembly of DNA, histone proteins, other associated proteins, and sometimes RNA, into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus. BP 2.20161341503226e-05 5 160 2830 1389949 0.00656404360012351 GO:0045815 positive regulation of gene expression, epigenetic Any epigenetic process that activates or increases the rate of gene expression. BP 2.28116198092911e-05 4 79 2830 1389949 0.00656404360012351 GO:0034728 nucleosome organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of one or more nucleosomes. BP 2.9424423190131e-05 5 170 2830 1389949 0.00657904469309028 GO:0006335 DNA replication-dependent nucleosome assembly The formation of nucleosomes on newly replicated DNA, coupled to strand elongation. BP 4.00115663350408e-05 3 32 2830 1389949 0.00657904469309028 GO:0034723 DNA replication-dependent nucleosome organization The formation or destruction of chromatin structures on newly replicated DNA, coupled to strand elongation. BP 4.00115663350408e-05 3 32 2830 1389949 0.00657904469309028 GO:0006323 DNA packaging Any process in which DNA and associated proteins are formed into a compact, orderly structure. BP 6.06779160994653e-05 5 198 2830 1389949 0.00873003517881057 GO:0000183 chromatin silencing at rDNA Repression of transcription of ribosomal DNA by altering the structure of chromatin. BP 7.29418507260426e-05 3 39 2830 1389949 0.00932845224285278 GO:0051290 protein heterotetramerization The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical. BP 9.12091762395457e-05 3 42 2830 1389949 0.0104981761851717 GO:0065004 protein-DNA complex assembly The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex. BP 0.000112875975087892 5 226 2830 1389949 0.0118109315751058 GO:0006325 chromatin organization Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin. BP 0.000173936758171004 8 743 2830 1389949 0.0165685245960744 GO:0071824 protein-DNA complex subunit organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex. BP 0.000187133640094672 5 252 2830 1389949 0.0165685245960744 GO:0071103 DNA conformation change A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule. BP 0.000293840245009892 5 278 2830 1389949 0.024157865857599 GO:0006303 double-strand break repair via nonhomologous end joining The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear. BP 0.000350552544874715 3 66 2830 1389949 0.0268990652767198 GO:0000726 non-recombinational repair A DNA repair process in which that does not require the exchange of genetic material between the broken DNA molecule and a homologous region of DNA. BP 0.00047143307335593 3 73 2830 1389949 0.0339137167145422 GO:0045653 negative regulation of megakaryocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation. BP 0.000620431320849765 2 18 2830 1389949 0.0420068500175341 GO:0050974 detection of mechanical stimulus involved in sensory perception The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception. BP 0.0011101600492881 2 24 2830 1389949 0.0709885675961446 GO:0045652 regulation of megakaryocyte differentiation Any process that modulates the frequency, rate or extent of megakaryocyte differentiation. BP 0.00162206093398073 2 29 2830 1389949 0.0836960307793393 GO:0006342 chromatin silencing Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin. BP 0.00175631109135702 3 115 2830 1389949 0.0836960307793393 GO:0051291 protein heterooligomerization The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer. BP 0.00184480911400375 3 117 2830 1389949 0.0836960307793393 GO:0040029 regulation of gene expression, epigenetic Any process that modulates the frequency, rate or extent of gene expression; the process is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence. BP 0.00199594196995989 4 256 2830 1389949 0.0836960307793393 GO:0046982 protein heterodimerization activity Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer. MF 0.00208030144478476 5 453 467 240069 0.0819755576537 GO:0098641 cadherin binding involved in cell-cell adhesion Any cadherin binding that occurs as part of the process of cell-cell adhesion. MF 0.00250618198734707 4 286 467 240069 0.0819755576537 GO:0098632 protein binding involved in cell-cell adhesion Any protein binding that is involved in cell-cell adhesion. MF 0.00283428196326912 4 296 467 240069 0.0819755576537 GO:0098631 protein binding involved in cell adhesion Any protein binding that is involved in cell adhesion. MF 0.00300884627089468 4 301 467 240069 0.0819755576537 GO:0045296 cadherin binding Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion. MF 0.00304461861712646 4 302 467 240069 0.0819755576537 GO:0019205 nucleobase-containing compound kinase activity Catalysis of the transfer of a phosphate group, usually from ATP or GTP, to a nucleobase, nucleoside, nucleotide or polynucleotide substrate. MF 0.00434843728804892 2 50 467 240069 0.0840697875689458 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. MF 0.00561479386063643 2 57 467 240069 0.0900856232502045 GO:0042393 histone binding Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity. MF 0.00575824235362616 3 184 467 240069 0.0900856232502045 GO:0000786 nucleosome A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures. CC 5.63465670017962e-06 5 102 960 396679 0.000894125012782294 GO:0044815 DNA packaging complex A protein complex that plays a role in the process of DNA packaging. CC 7.45104177318578e-06 5 108 960 396679 0.000894125012782294 GO:0032993 protein-DNA complex A macromolecular complex containing both protein and DNA molecules. CC 7.15370957310218e-05 5 173 960 396679 0.00572296765848174 GO:0000785 chromatin The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. CC 0.00089030569014591 6 450 960 396679 0.0534183414087546 GO:0035327 transcriptionally active chromatin The ordered and organized complex of DNA and protein that forms regions of the chromosome that are being actively transcribed. CC 0.00119167999449008 2 21 960 396679 0.0572006397355238