go.id go.term Definition Ontology pvalue count.InDataset count.InGenome totaltermInDataset totaltermInGenome BH.adjusted.p.value GO:0006334 nucleosome assembly The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA. BP 5.85700515083009e-06 4 144 1087 1389949 0.00236987802647227 GO:0031497 chromatin assembly The assembly of DNA, histone proteins, other associated proteins, and sometimes RNA, into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus. BP 8.8762013343209e-06 4 160 1087 1389949 0.00236987802647227 GO:0034728 nucleosome organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of one or more nucleosomes. BP 1.12672489372691e-05 4 170 1087 1389949 0.00236987802647227 GO:0006333 chromatin assembly or disassembly The formation or destruction of chromatin structures. BP 1.57009047381641e-05 4 185 1087 1389949 0.00247681772244539 GO:0006323 DNA packaging Any process in which DNA and associated proteins are formed into a compact, orderly structure. BP 2.04800660122003e-05 4 198 1087 1389949 0.00258458433073968 GO:0065004 protein-DNA complex assembly The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex. BP 3.42934653283044e-05 4 226 1087 1389949 0.00360652943702668 GO:0071824 protein-DNA complex subunit organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex. BP 5.2309805473034e-05 4 252 1087 1389949 0.00471535532192635 GO:0071103 DNA conformation change A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule. BP 7.64086615860209e-05 4 278 1087 1389949 0.0060267331825974 GO:0050974 detection of mechanical stimulus involved in sensory perception The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception. BP 0.000166725077620847 2 24 1087 1389949 0.0116892804420838 GO:0006335 DNA replication-dependent nucleosome assembly The formation of nucleosomes on newly replicated DNA, coupled to strand elongation. BP 0.000298378802329862 2 32 1087 1389949 0.0171160931154675 GO:0034723 DNA replication-dependent nucleosome organization The formation or destruction of chromatin structures on newly replicated DNA, coupled to strand elongation. BP 0.000298378802329862 2 32 1087 1389949 0.0171160931154675 GO:0000183 chromatin silencing at rDNA Repression of transcription of ribosomal DNA by altering the structure of chromatin. BP 0.000444145641580754 2 39 1087 1389949 0.023223899170591 GO:0050982 detection of mechanical stimulus The series of events by which a mechanical stimulus is received and converted into a molecular signal. BP 0.000490987020515511 2 41 1087 1389949 0.023223899170591 GO:0051290 protein heterotetramerization The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical. BP 0.000515268761312637 2 42 1087 1389949 0.023223899170591 GO:0034622 cellular macromolecular complex assembly The aggregation, arrangement and bonding together of a set of macromolecules to form a complex, carried out at the cellular level. BP 0.00105938762601492 5 961 1087 1389949 0.0417795995009634 GO:0051276 chromosome organization A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome. BP 0.00153146334732198 4 618 1087 1389949 0.0548084894593765 GO:0045815 positive regulation of gene expression, epigenetic Any epigenetic process that activates or increases the rate of gene expression. BP 0.00180879477202196 2 79 1087 1389949 0.0600710263760977 GO:0006325 chromatin organization Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin. BP 0.00296879074521765 4 743 1087 1389949 0.0857201994143353 GO:0006342 chromatin silencing Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin. BP 0.00377730258938887 2 115 1087 1389949 0.0930022836858168 GO:0051291 protein heterooligomerization The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer. BP 0.00390637682013502 2 117 1087 1389949 0.0930022836858168 GO:0009581 detection of external stimulus The series of events in which an external stimulus is received by a cell and converted into a molecular signal. BP 0.00479454697019137 2 130 1087 1389949 0.0930022836858168 GO:0045814 negative regulation of gene expression, epigenetic Any epigenetic process that stops, prevents or reduces the rate of gene expression. BP 0.00486636832409773 2 131 1087 1389949 0.0930022836858168 GO:0009582 detection of abiotic stimulus The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal. BP 0.00501149812766099 2 133 1087 1389949 0.0930022836858168 GO:0006461 protein complex assembly The aggregation, arrangement and bonding together of a set of components to form a protein complex. BP 0.00508025515429096 5 1387 1087 1389949 0.0930022836858168 GO:0070271 protein complex biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a protein complex. Includes the synthesis of non-protein components, and those protein modifications that are involved in synthesis or assembly of the complex. BP 0.00508025515429096 5 1387 1087 1389949 0.0930022836858168 GO:0051262 protein tetramerization The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits. BP 0.00515860527575846 2 135 1087 1389949 0.0930022836858168 GO:0032200 telomere organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of telomeres, terminal regions of a linear chromosome that include the telomeric DNA repeats and associated proteins. BP 0.00592357331271785 2 145 1087 1389949 0.0960237720256103 GO:0031490 chromatin DNA binding Interacting selectively and non-covalently with DNA that is assembled into chromatin. MF 0.00278954526856071 2 97 191 240069 0.0731087733414636 GO:0008144 drug binding Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease. MF 0.0029033437215505 2 99 191 240069 0.0731087733414636 GO:0043566 structure-specific DNA binding Interacting selectively and non-covalently with DNA of a specific structure or configuration e.g. triplex DNA binding or bent DNA binding. MF 0.00523685908816874 2 134 191 240069 0.0750051261178403 GO:0046982 protein heterodimerization activity Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer. MF 0.00586996639183098 3 453 191 240069 0.0750051261178403 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters. MF 0.00792776999096112 1 10 191 240069 0.0759744624133774 GO:0043176 amine binding Interacting selectively and non-covalently with any organic compound that is weakly basic in character and contains an amino or a substituted amino group. MF 0.00792776999096112 1 10 191 240069 0.0759744624133774 GO:0051378 serotonin binding Interacting selectively and non-covalently with serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. MF 0.00792776999096112 1 10 191 240069 0.0759744624133774 GO:0010314 phosphatidylinositol-5-phosphate binding Interacting selectively and non-covalently with phosphatidylinositol-5-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 5' position. MF 0.00871710009702553 1 11 191 240069 0.0771128085506105 GO:0042393 histone binding Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity. MF 0.00964042051743016 2 184 191 240069 0.0791891685360334 GO:0000786 nucleosome A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures. CC 4.45358684737436e-06 4 102 411 396679 0.000338125937321979 GO:0044815 DNA packaging complex A protein complex that plays a role in the process of DNA packaging. CC 5.58885846813188e-06 4 108 411 396679 0.000338125937321979 GO:0032993 protein-DNA complex A macromolecular complex containing both protein and DNA molecules. CC 3.56420005282e-05 4 173 411 396679 0.00143756068797073 GO:0000788 nuclear nucleosome A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA in the nucleus into higher order structures. CC 0.000897069452702952 2 42 411 396679 0.0271363509442643 GO:0000785 chromatin The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. CC 0.00133109335558989 4 450 411 396679 0.0322124592052753 GO:0044454 nuclear chromosome part Any constituent part of a nuclear chromosome, a chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact. CC 0.0018953037619157 4 496 411 396679 0.0382219591986333 GO:0000228 nuclear chromosome A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact. CC 0.00240589831804843 4 530 411 396679 0.0415876709262657 GO:0000790 nuclear chromatin The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus. CC 0.00384601745670117 3 298 411 396679 0.056946488447814 GO:0000784 nuclear chromosome, telomeric region The terminal region of a linear nuclear chromosome that includes the telomeric DNA repeats and associated proteins. CC 0.00847137844678225 2 132 411 396679 0.056946488447814 GO:0044427 chromosomal part Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. CC 0.0100099244730152 4 798 411 396679 0.060560043061742 GO:0000781 chromosome, telomeric region The terminal region of a linear chromosome that includes the telomeric DNA repeats and associated proteins. CC 0.0126668367058418 2 163 411 396679 0.0729851067336599 GO:0005694 chromosome A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. CC 0.0152738012063039 4 906 411 396679 0.0840059066346714