Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Unique_M2_collapsed_to_symbols.Unique_M2.cls #KO_M2_versus_WT_M2.Unique_M2.cls #KO_M2_versus_WT_M2_repos |
| Phenotype | Unique_M2.cls#KO_M2_versus_WT_M2_repos |
| Upregulated in class | WT_M2 |
| GeneSet | REACTOME_MEMBRANE_TRAFFICKING |
| Enrichment Score (ES) | -0.35144874 |
| Normalized Enrichment Score (NES) | -1.7271334 |
| Nominal p-value | 0.009433962 |
| FDR q-value | 0.1377026 |
| FWER p-Value | 0.192 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | RAB33B | "RAB33B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:16075]" | 27 | 2.635 | -0.0350 | No | ||
| 2 | AP3S1 | adaptor related protein complex 3 subunit sigma 1 [Source:HGNC Symbol;Acc:HGNC:2013] | 52 | 2.039 | -0.0714 | No | ||
| 3 | DNM3 | dynamin 3 [Source:HGNC Symbol;Acc:HGNC:29125] | 97 | 1.109 | -0.1841 | No | ||
| 4 | CD59 | CD59 molecule (CD59 blood group) [Source:HGNC Symbol;Acc:HGNC:1689] | 105 | 0.975 | -0.1881 | No | ||
| 5 | HSPA8 | heat shock protein family A (Hsp70) member 8 [Source:HGNC Symbol;Acc:HGNC:5241] | 115 | 0.794 | -0.2013 | No | ||
| 6 | MAN1C1 | mannosidase alpha class 1C member 1 [Source:HGNC Symbol;Acc:HGNC:19080] | 151 | -1.543 | -0.2794 | No | ||
| 7 | ITSN1 | intersectin 1 [Source:HGNC Symbol;Acc:HGNC:6183] | 176 | -1.733 | -0.3211 | Yes | ||
| 8 | SPTAN1 | "spectrin alpha, non-erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11273]" | 177 | -1.740 | -0.2907 | Yes | ||
| 9 | FTH1 | ferritin heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:3976] | 180 | -1.752 | -0.2661 | Yes | ||
| 10 | CBL | Cbl proto-oncogene [Source:HGNC Symbol;Acc:HGNC:1541] | 182 | -1.762 | -0.2383 | Yes | ||
| 11 | DAB2 | DAB adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:2662] | 205 | -1.868 | -0.2717 | Yes | ||
| 12 | KIF16B | kinesin family member 16B [Source:HGNC Symbol;Acc:HGNC:15869] | 207 | -1.877 | -0.2418 | Yes | ||
| 13 | TBC1D4 | TBC1 domain family member 4 [Source:HGNC Symbol;Acc:HGNC:19165] | 220 | -1.924 | -0.2442 | Yes | ||
| 14 | AP1B1 | adaptor related protein complex 1 subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:554] | 232 | -1.973 | -0.2427 | Yes | ||
| 15 | MYO5A | myosin VA [Source:HGNC Symbol;Acc:HGNC:7602] | 242 | -2.009 | -0.2346 | Yes | ||
| 16 | KIAA0319 | KIAA0319 [Source:HGNC Symbol;Acc:HGNC:21580] | 243 | -2.023 | -0.1992 | Yes | ||
| 17 | MYO1C | myosin IC [Source:HGNC Symbol;Acc:HGNC:7597] | 266 | -2.110 | -0.2284 | Yes | ||
| 18 | TF | transferrin [Source:HGNC Symbol;Acc:HGNC:11740] | 288 | -2.221 | -0.2526 | Yes | ||
| 19 | EXOC3 | exocyst complex component 3 [Source:HGNC Symbol;Acc:HGNC:30378] | 295 | -2.265 | -0.2310 | Yes | ||
| 20 | NSF | "N-ethylmaleimide sensitive factor, vesicle fusing ATPase [Source:HGNC Symbol;Acc:HGNC:8016]" | 302 | -2.308 | -0.2087 | Yes | ||
| 21 | DYNC1H1 | dynein cytoplasmic 1 heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:2961] | 306 | -2.341 | -0.1768 | Yes | ||
| 22 | EPS15L1 | epidermal growth factor receptor pathway substrate 15 like 1 [Source:HGNC Symbol;Acc:HGNC:24634] | 308 | -2.353 | -0.1386 | Yes | ||
| 23 | SNX9 | sorting nexin 9 [Source:HGNC Symbol;Acc:HGNC:14973] | 315 | -2.402 | -0.1146 | Yes | ||
| 24 | KIF13B | kinesin family member 13B [Source:HGNC Symbol;Acc:HGNC:14405] | 316 | -2.403 | -0.0726 | Yes | ||
| 25 | FNBP1 | formin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17069] | 323 | -2.477 | -0.0473 | Yes | ||
| 26 | DNM2 | dynamin 2 [Source:HGNC Symbol;Acc:HGNC:2974] | 332 | -2.635 | -0.0252 | Yes | ||
| 27 | RAB3GAP2 | RAB3 GTPase activating non-catalytic protein subunit 2 [Source:HGNC Symbol;Acc:HGNC:17168] | 342 | -2.897 | -0.0016 | Yes | ||
| 28 | TRAPPC12 | trafficking protein particle complex 12 [Source:HGNC Symbol;Acc:HGNC:24284] | 346 | -3.009 | 0.0420 | Yes |
