Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Unique_M2_collapsed_to_symbols.Unique_M2.cls #KO_M2_versus_WT_M2.Unique_M2.cls #KO_M2_versus_WT_M2_repos |
| Phenotype | Unique_M2.cls#KO_M2_versus_WT_M2_repos |
| Upregulated in class | WT_M2 |
| GeneSet | REACTOME_DISEASE |
| Enrichment Score (ES) | -0.26855218 |
| Normalized Enrichment Score (NES) | -1.4869705 |
| Nominal p-value | 0.06507937 |
| FDR q-value | 0.17389761 |
| FWER p-Value | 0.557 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | SLC4A4 | solute carrier family 4 member 4 [Source:HGNC Symbol;Acc:HGNC:11030] | 23 | 2.720 | -0.0381 | No | ||
| 2 | SLC3A1 | solute carrier family 3 member 1 [Source:HGNC Symbol;Acc:HGNC:11025] | 44 | 2.169 | -0.0736 | No | ||
| 3 | VCAN | versican [Source:HGNC Symbol;Acc:HGNC:2464] | 48 | 2.110 | -0.0567 | No | ||
| 4 | PRKX | protein kinase X-linked [Source:HGNC Symbol;Acc:HGNC:9441] | 62 | 1.855 | -0.0743 | No | ||
| 5 | SLC22A5 | solute carrier family 22 member 5 [Source:HGNC Symbol;Acc:HGNC:10969] | 64 | 1.833 | -0.0547 | No | ||
| 6 | FASLG | Fas ligand [Source:HGNC Symbol;Acc:HGNC:11936] | 76 | 1.421 | -0.0714 | No | ||
| 7 | RPS15 | ribosomal protein S15 [Source:HGNC Symbol;Acc:HGNC:10388] | 128 | -1.232 | -0.2154 | No | ||
| 8 | NUP54 | nucleoporin 54 [Source:HGNC Symbol;Acc:HGNC:17359] | 146 | -1.477 | -0.2502 | Yes | ||
| 9 | SND1 | staphylococcal nuclease and tudor domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30646] | 148 | -1.486 | -0.2349 | Yes | ||
| 10 | GAB1 | GRB2 associated binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4066] | 149 | -1.523 | -0.2159 | Yes | ||
| 11 | ELOA | elongin A [Source:HGNC Symbol;Acc:HGNC:11620] | 150 | -1.542 | -0.1968 | Yes | ||
| 12 | CAPNS1 | calpain small subunit 1 [Source:HGNC Symbol;Acc:HGNC:1481] | 154 | -1.565 | -0.1867 | Yes | ||
| 13 | CALR | calreticulin [Source:HGNC Symbol;Acc:HGNC:1455] | 158 | -1.600 | -0.1762 | Yes | ||
| 14 | KPNB1 | karyopherin subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:6400] | 161 | -1.640 | -0.1620 | Yes | ||
| 15 | PLCG2 | phospholipase C gamma 2 [Source:HGNC Symbol;Acc:HGNC:9066] | 174 | -1.724 | -0.1781 | Yes | ||
| 16 | CBL | Cbl proto-oncogene [Source:HGNC Symbol;Acc:HGNC:1541] | 182 | -1.762 | -0.1781 | Yes | ||
| 17 | GYG1 | glycogenin 1 [Source:HGNC Symbol;Acc:HGNC:4699] | 189 | -1.781 | -0.1747 | Yes | ||
| 18 | SDC4 | syndecan 4 [Source:HGNC Symbol;Acc:HGNC:10661] | 191 | -1.799 | -0.1554 | Yes | ||
| 19 | OS9 | OS9 endoplasmic reticulum lectin [Source:HGNC Symbol;Acc:HGNC:16994] | 197 | -1.812 | -0.1485 | Yes | ||
| 20 | RNF213 | ring finger protein 213 [Source:HGNC Symbol;Acc:HGNC:14539] | 208 | -1.878 | -0.1564 | Yes | ||
| 21 | NCKAP1L | NCK associated protein 1 like [Source:HGNC Symbol;Acc:HGNC:4862] | 209 | -1.881 | -0.1331 | Yes | ||
| 22 | RXFP1 | relaxin family peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:19718] | 213 | -1.892 | -0.1189 | Yes | ||
| 23 | IQGAP1 | IQ motif containing GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:6110] | 230 | -1.969 | -0.1445 | Yes | ||
| 24 | AP1B1 | adaptor related protein complex 1 subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:554] | 232 | -1.973 | -0.1231 | Yes | ||
| 25 | MYO5A | myosin VA [Source:HGNC Symbol;Acc:HGNC:7602] | 242 | -2.009 | -0.1262 | Yes | ||
| 26 | NUP205 | nucleoporin 205 [Source:HGNC Symbol;Acc:HGNC:18658] | 246 | -2.030 | -0.1104 | Yes | ||
| 27 | RPL7 | ribosomal protein L7 [Source:HGNC Symbol;Acc:HGNC:10363] | 252 | -2.049 | -0.1005 | Yes | ||
| 28 | PSEN1 | presenilin 1 [Source:HGNC Symbol;Acc:HGNC:9508] | 256 | -2.070 | -0.0842 | Yes | ||
| 29 | DOCK2 | dedicator of cytokinesis 2 [Source:HGNC Symbol;Acc:HGNC:2988] | 263 | -2.089 | -0.0769 | Yes | ||
| 30 | MYO1C | myosin IC [Source:HGNC Symbol;Acc:HGNC:7597] | 266 | -2.110 | -0.0570 | Yes | ||
| 31 | GNAI2 | G protein subunit alpha i2 [Source:HGNC Symbol;Acc:HGNC:4385] | 269 | -2.121 | -0.0369 | Yes | ||
| 32 | EP300 | E1A binding protein p300 [Source:HGNC Symbol;Acc:HGNC:3373] | 276 | -2.147 | -0.0289 | Yes | ||
| 33 | MYO9B | myosin IXB [Source:HGNC Symbol;Acc:HGNC:7609] | 278 | -2.159 | -0.0052 | Yes | ||
| 34 | TNKS | tankyrase [Source:HGNC Symbol;Acc:HGNC:11941] | 286 | -2.205 | 0.0003 | Yes | ||
| 35 | HSP90AB1 | heat shock protein 90 alpha family class B member 1 [Source:HGNC Symbol;Acc:HGNC:5258] | 296 | -2.265 | 0.0004 | Yes | ||
| 36 | MRC1 | mannose receptor C-type 1 [Source:HGNC Symbol;Acc:HGNC:7228] | 299 | -2.288 | 0.0226 | Yes | ||
| 37 | DYNC1H1 | dynein cytoplasmic 1 heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:2961] | 306 | -2.341 | 0.0329 | Yes | ||
| 38 | RPS10 | ribosomal protein S10 [Source:HGNC Symbol;Acc:HGNC:10383] | 313 | -2.397 | 0.0439 | Yes | ||
| 39 | TAF4 | TATA-box binding protein associated factor 4 [Source:HGNC Symbol;Acc:HGNC:11537] | 317 | -2.411 | 0.0645 | Yes | ||
| 40 | GAA | "glucosidase alpha, acid [Source:HGNC Symbol;Acc:HGNC:4065]" | 324 | -2.486 | 0.0767 | Yes | ||
| 41 | TLN1 | talin 1 [Source:HGNC Symbol;Acc:HGNC:11845] | 331 | -2.630 | 0.0906 | Yes |
