Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Unique_M2_collapsed_to_symbols.Unique_M2.cls #KO_M2_versus_WT_M2.Unique_M2.cls #KO_M2_versus_WT_M2_repos |
| Phenotype | Unique_M2.cls#KO_M2_versus_WT_M2_repos |
| Upregulated in class | WT_M2 |
| GeneSet | REACTOME_CELL_CYCLE |
| Enrichment Score (ES) | -0.27179733 |
| Normalized Enrichment Score (NES) | -1.1269155 |
| Nominal p-value | 0.320598 |
| FDR q-value | 0.4644676 |
| FWER p-Value | 0.98 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CHTF18 | chromosome transmission fidelity factor 18 [Source:HGNC Symbol;Acc:HGNC:18435] | 4 | 3.588 | 0.0898 | No | ||
| 2 | HAUS3 | HAUS augmin like complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:28719] | 47 | 2.141 | 0.0283 | No | ||
| 3 | CEP164 | centrosomal protein 164 [Source:HGNC Symbol;Acc:HGNC:29182] | 49 | 2.089 | 0.0844 | No | ||
| 4 | ATR | ATR serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:882] | 112 | 0.869 | -0.0712 | No | ||
| 5 | GINS4 | GINS complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:28226] | 140 | -1.404 | -0.1100 | No | ||
| 6 | NUP54 | nucleoporin 54 [Source:HGNC Symbol;Acc:HGNC:17359] | 146 | -1.477 | -0.0828 | No | ||
| 7 | KPNB1 | karyopherin subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:6400] | 161 | -1.640 | -0.0771 | No | ||
| 8 | SDCCAG8 | serologically defined colon cancer antigen 8 [Source:HGNC Symbol;Acc:HGNC:10671] | 162 | -1.649 | -0.0305 | No | ||
| 9 | NUP205 | nucleoporin 205 [Source:HGNC Symbol;Acc:HGNC:18658] | 246 | -2.030 | -0.2144 | Yes | ||
| 10 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 248 | -2.031 | -0.1599 | Yes | ||
| 11 | EP300 | E1A binding protein p300 [Source:HGNC Symbol;Acc:HGNC:3373] | 276 | -2.147 | -0.1777 | Yes | ||
| 12 | ORC5 | origin recognition complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:8491] | 280 | -2.160 | -0.1253 | Yes | ||
| 13 | TOPBP1 | DNA topoisomerase II binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17008] | 283 | -2.190 | -0.0692 | Yes | ||
| 14 | SYNE2 | spectrin repeat containing nuclear envelope protein 2 [Source:HGNC Symbol;Acc:HGNC:17084] | 284 | -2.196 | -0.0071 | Yes | ||
| 15 | HSP90AB1 | heat shock protein 90 alpha family class B member 1 [Source:HGNC Symbol;Acc:HGNC:5258] | 296 | -2.265 | 0.0249 | Yes | ||
| 16 | DYNC1H1 | dynein cytoplasmic 1 heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:2961] | 306 | -2.341 | 0.0650 | Yes | ||
| 17 | CDK11B | cyclin dependent kinase 11B [Source:HGNC Symbol;Acc:HGNC:1729] | 351 | -3.152 | 0.0262 | Yes |
